Arsenal manager Arsene Wenger says the club will follow their "own recommendations" over Mesut Ozil's knee injury.
According to the German Football Association the midfielder is expected to be on the sidelines for 12 weeks, including six weeks of immobilisation of the knee joint.
"When he arrived with the German national team, they didn't think it was a lot at the start," Wenger told the club's official website.
"He was supposed to practice on Wednesday but, in the end, he said that wasn't possible for him.
"Then he had a scan and it was bad news. We have our own specialist giving us his opinion after reading the scan and examining Mesut. We will follow our own recommendations."
The Frenchman did however confirm that a number of key players will be back after the international break, including striker Theo Walcott.
"Theo [Walcott] is not too far away now. Serge [Gnabry] has been out for a long, long time and Theo has also been out for nine months, so it's good to see them back," said Wenger.
"They've worked very hard and they're very dedicated. They are back in the group on a daily basis and that's very good news.
"For [Aaron] Ramsey it's day 13 today and I think it will be day 21 before he is back into training. [Mikel] Arteta may be back with the group late next week."