Manchester United winger Ashley Young is expected to be sidelined for a "long time", manager Louis van Gaal revealed.
The 30-year-old will undergo groin surgery after suffering the injury during the 1-0 win against Liverpool.
Defender Phil Jones and midfielder Bastian Schweinsteiger will also miss today's game against Southampton.
"Ashley Young has a severe groin injury, it shall be operated on, so he's [out] for a long time," van Gaal revealed.
"It's unbelievable, but we're not lucky with that. [Phil] Jones and [Bastian] Schweinsteiger cannot come back this weekend. You can count it and we have seven injuries.
"[Cameron Borthwick-Jackson replacing Young?] He's more or less a very good player for his age.
"He has shown already that he can cope with the pressure but, with youth players, the question is always: are they consistent? One match or a substitution is always good, but consistency is always the question mark.
"I think that he [Adnan Januzaj] is available.
"He made his work in the training sessions and he has played one match, which is not much of course. He needs to play more matches, but he is available."