Manchester United boss Louis van Gaal is ready to make a move for Marco Reus, Gonzalo Higuain and Nicolas Gaitan, Metro reports.
For the striker, the Red Devils will have to fend off competition from Juventus and Atletico Madrid.
Higuain's brother and agent, Nicolas, will be in Italy next week to meet president Aurelio De Laurentiis and it seems unlikely that the 27-year-old will continue with the Italians next season if they fail to qualify for the Champions League play-offs.
Borussia Dortmund's Marco Reus is also linked with Arsenal with Juventus and Real Madrid also ready to make a move for the 25-year-old.
But the Red Devils are determined to fight to bring the talented midfielder to Old Trafford and are ready to offer £50m.
And according to A Bola, a £21m offer is to be made to secure the services of Benfica midfielder Nico Gaitan.