Manchester City manager Manuel Pellegrini says attacking midfielder Samir Nasri is out injured but David Silva, Bacary Sagna, Gael Clichy are all back to face Stoke City.
City's hopes to finish in the Top Four suffered a setback after they could only manage a draw away at Newcastle United and will be desperate to take all three points today against Stoke City.
And the Chilean confirmed that the focus is on the Premier League and not week's Champions League game against Real Madrid.
"Only Samir Nasri is out, he isn't 100 per cent yet," Pellegrini said on Friday.
"I hope he'll be back for the next game [against Southampton]. The rest of the squad is fit.
"It's very important we're in the Champions League semi-final, but that doesn't mean we're not worried about the Premier League.
"All the big teams must try to reach the final of the Champions League and be involved in domestic games and titles. It is very important to get a spot in next season's Champions League.
"It was exactly the same against PSG.
"We had important Premier League games then and I said the best way to prepare is to win your games, as that gives you trust in the players.
"The best way to prepare for Tuesday is to beat Stoke, to score goals, keep a clean sheet, and that will help to prepare.
"The risk of an injury is always there. For big teams you can't choose one competition. See the big teams, they are involved domestic and European titles. If they are eliminated, that can happen."