Manchester City boss Manuel Pellegrini says five key players will not feature against Newcastle United on Saturday afternoon.
The Citizens registered their first Champions League win of the campaign in mid-week away at Borussia Monchengladbach.
And they will be eager to get back on winning terms in the Premier League when they take on the Magpies at the St. James' Park.
"We always expect to win at home but away also," Pellegrini told reporters.
"We want to win everywhere. We have to play in the same way, in the same style.
"Tomorrow we have a tough game against Newcastle. They played very well against Chelsea and here in Manchester against United.
"We are not thinking of the top of the table at this moment – just to have a strong performance. It's important to be at the top in May.
"We know we are going to have eight or nine players defending so we have to create the space.
"Vincent Kompany, Clichy, Delph, Nasri and Toure are injured. Mangala is on the squad list and so are Kelechi and Bony.
"Kompany's calf is still injured – we'll see if he's fit after the international break.
"It's not been a normal situation to have so many injuries – against Sunderland we had 11 injured, then it's been seven or eight. I hope after this break, most of them will be fit.
"I never complain about the players who can't play. I don't think that one name can change the performance of this team. We also win a lot of games without Vincent.
"He's an important player for us of course – we hope we will play again soon of course."