Manchester City manager Manuel Pellegrini says a number of key players are back in the squad.
Defender Vincent Kompany, goalkeeper Joe Hart and midfielder Samir Nasri have all recovered from injury and could feature against Spurs in tomorrow's early kick-off.
"At this moment, Mangala, Clichy, Delph, Silva, Bony and Kelechi are the six players injured," Pellegrini told reporters.
"Kompany is back, Hart is back, Nasri is back.
"I'm not 100% sure [when Mangala and Silva will be back], it depends on how they improve – maybe David can be fit for next Championship game, we'll see next week. For Mangala, it will be difficult for him to be fit before the international break.
"It's important for the team to have Vincent back. He's just recovering, he's the captain and he played well at the start of the season. Not just defending but he scored three goals also.
"We've had a lot of different injuries so it's not just one reason but that's why it's important to have a squad."